Why Cannabinoids Synthetic Side Effects Are Unsafe? Truthful Facts About Spice
What are synthetic cannabinoids? Today, we will learn about the best synthetic cannabinoids, which are banned.
Synthetic cannabinoids are substances that are agonists of the CB1 and CB2 cannabinoid receptors.
Spice is often proposed as legal synthetic cannabinoids and a safe alternative to smoking marijuana. However, their use is associated with many serious side effects. The new review contains clinical cases associated with the use of cannabinoids synthetic.
Synthetic Cannabinoids Before the 1990s
The synthesis of classic cannabinoids began in the 1960s after clarifying the chemical structure of THC. Cyclohexylphenols (CP series) was first synthesized by the American pharmaceutical company Pfizer in the 1970s and 1980s.
Synthetic Cannabinoids In the 1990s
A significant portion of JWH synthetic cannabinoids was synthesized by the American chemist John W. Huffman from 1995 to the present.
Synthetic Cannabinoids After the 2000s
Synthetic cannabinoids, synthesized mainly in China, are gaining popularity. On the market, they are represented mainly by “Spice” – smoking mixtures, which include a cannabinoid known only to manufacturers.
The synthetic cannabinoids that make up the Spice smoking blends were not on the international lists of controlled drugs and were synthetic cannabinoids legal. At the end of 2008 – 2009, smoking mixtures were examined, after the discovery of synthetic cannabinoids in them, the authorities of some countries began to take measures to ban these compounds and create a list of synthetic cannabinoids dea.
Dangers of Synthetic Cannabinoid
CDC synthetic cannabinoids come in two forms. They are either sprayed onto dried plants, and the resulting mixture can then be smoked like tobacco, or incorporated into evaporated liquids to be inhaled.
Referring to substances that are marketed under the name “strongest k2 Spice” or “mamba drug,” Paul Prather, Cellular and Molecular Pharmacology Specialist at UAMS, explained: “In the United States around 2007, people started going to emergency rooms who said they smoked marijuana. However, they had strange withdrawal symptoms of synthetic cannabinoids, unlike the effects of marijuana use.”
If you’re wondering what is mamba drug, then this is the slang name for a synthetic cannabinoid.
The review was compiled using the available synthetic cannabinoid literature and demonstrated that these erowid synthetic cannabinoids are not like marijuana and cannot be considered an alternative. In fact, these are completely different drugs with numerous dangerous and fatal effects.
The Action of Synthetic Cannabinoid
The way synthetic cannabinoids work is similar in many ways to how marijuana works. However, as scientists note, liquid synthetic cannabinoids affect CB1 receptors much more strongly than tetrahydrocannabinol. In addition, since the formula of synthetic substances differs from the components of conventional marijuana, they are theoretically capable of acting on other receptors, as yet unknown.
The list of banned synthetic cannabinoids is very extensive and changes every year, so it is best to search on the Internet for a complete table of substances with all names.
Synthetic Cannabinoids Side Effects
The data collected to date suggest that new synthetic cannabinoids are much more toxic and more dangerous than marijuana. In particular, they affect the nervous and cardiovascular systems, and negatively affect the kidneys and the gastrointestinal tract. The negative health effects from synthetic cannabinoids include:
- Kidney damage;
- Pressure increase;
- Chest pain;
- Ischemic stroke.
Common side effects of synthetic cannabinoids included prolonged, intense vomiting, anxiety, panic attacks, and irritability. In addition, patients developed extremely severe psychosis against the background of the use of synthetic cannabinoids in the presence of a predisposition.
In addition, in the period from 2011 to 2014, in the United States, 20 deaths have been reported from the use of this synthetic substance, which confirms its high toxicity and danger. By the way, there were no reports of deaths due to the use of marijuana during this period. You can draw the corresponding conclusions that there are currently no safe synthetic cannabinoids.
It is important to know that if you use synthetic cannabinoids, you are more likely to develop severe withdrawal symptoms and a strong dependence on the substance.
Synthetic cannabinoids are not detected in routine assays. Therefore, they are especially popular among people who would like to avoid detection in synthetic cannabinoids urine test or in a synthetic cannabinoids drug test, for example, among adolescents or military personnel. These users usually buy drugs over the Internet, often without knowing what exactly they are buying, since the composition of the mixture in each subsequent purchase may be different.
“Changes can affect not only the amount of active substance but also its formula itself,” says co-author of the review William Fantegrossi, an expert in behavioral pharmacology. In one mixture, you can usually find from 3 to 5 of the most different types of synthetic drugs, possibly very toxic, which are included in the banned synthetic cannabinoids list. The authors of the blog tried to tell you what are synthetic cannabinoids and the side effects of their use, how they are dangerous for the body in comparison with ordinary marijuana, and how people avoid testing for synthetic cannabinoids.
- We see you've got what you wanted! Give a feedback!
- We already spotted your angry eyes. Come on, spell it.
All provided content on the blog is presented exclusively for adults (21+ years old)
The content on this channel does not form a professional opinion, recommendation, substitute for consulting a specialist, or receiving medical advice. Cannabis is a dangerous drug, as defined in the Dangerous Drugs Ordinance, for all that assumes. Four Hundred and Twenty does not encourage or recommend consuming any substance and will not be responsible for any such use.
More in Strains
Are There Hash Benefits? The Truth About The Dangers And Addiction Of Hash Drug
The term hash drug includes a number of hemp-derived drugs. Like other drugs, hashish has a negative effect on various...
What Is The Difference Between Medical And Recreational Weed? Find Out What Is Better To Use
Today we’ll talk about what makes cannabis different. The main difference between medical and recreational weed is its legal status....
Amber Trichomes Or Milky Trichomes. Which Are The Best? Find Out Interesting Facts
Trichomes are small, mushroom-shaped, transparent processes that grow on cannabis buds. In fact, these are glands that secrete resin. They...