Problem – alcohol addiction. Solution – CBD!
The hemp medicinal substance reduces the need for alcohol and its harmful effects on the body.
Cannabidiol (CBD), a non-psychoactive component of marijuana and technical cannabis, may be beneficial to people who abuse alcohol, according to a recent review of scientific publications.
CBD not only helps reduce alcohol consumption but also provides some protection for the liver and brain.
Scientists from France and Belgium reviewed 26 studies published between 1974 and June 2018 that examined the effects of CBD on animals receiving an ethanol dose. Several studies have shown that CBD can reduce alcohol consumption. For example, in one of them, the researchers found that mice injected with CBD were less motivated to make an effort (push the lever) to obtain an 8% ethanol solution.
Experimental studies agree that CBD reduces the overall level of alcohol consumption in animal models by reducing ethanol consumption, ethanol motivation, relapses, and by reducing anxiety and impulsivity.
Other studies have shown that mice that have been regularly treated with a non-psychological cannabis drug are also less likely to relapse after being rid of alcohol, even when they are stressed. The review authors write that CBD can have a significant impact on people’s alcohol consumption.
CBD impact on alcohol-induced liver inflammation
The review also highlights evidence that CBD can have an impact on alcohol-induced liver inflammation. One study found that the liver of mice that received CBD every 12 hours for five days before forced intoxication by alcohol was less damaged than those of mice that did not receive CBD.
CBD has valuable therapeutic properties for ethanol-induced liver damage, and therapeutic effects are achieved through a variety of mechanisms, including reducing oxidative stress, controlling inflammation, and the death of certain cells responsible for large amounts of scar tissue.
Finally, CBD can also provide additional protection to certain areas of the brain that are damaged by alcohol consumption. One study found that the brain of rats that consumed alcohol and received CBD lost significantly fewer cells in the hippocampus and entorhinal cortex. CBD acted as a “neuroprotective antioxidant” in these rats. In another experiment, CBD also restored neurological and cognitive functions in rats with acute hepatic failure.
The authors suggest that these therapeutic effects of CBD may be associated with the complex effects of the substance on CB2 receptors, which are located throughout the body.
Currently, as noted in the review, drugs that can help people avoid addiction to alcohol are not effective enough, and new therapeutic developments are needed. Moreover, no drugs that reduce the harm of alcohol to the brain and liver have ever been studied.
Also, the authors conclude that CBD may have much more positive effects, including antiepileptic, cardioprotective, anxiolytic, or analgesic effects in alcohol-dependent patients. Thus, clinical trials are essential to examine the potential for CBD in alcohol-related disorders.
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